Description

Malonaldehyde-1,3-D2 Bis(Diethyl Acetal) is a deuterated derivative of malonaldehyde bis(diethyl acetal), serving as a crucial isotopically labeled building block and analytical standard. This compound is essential for researchers and manufacturers requiring precise molecular tracking and metabolic pathway elucidation in complex chemical and biological systems. It is primarily utilized in advanced pharmaceutical research, organic synthesis, and analytical chemistry for applications such as NMR spectroscopy and the development of labeled active pharmaceutical ingredients (APIs).

Application

• Deuterated NMR Spectroscopy Standard: Used as an internal standard or reference compound in nuclear magnetic resonance (NMR) studies for solvent suppression and chemical shift calibration.
• Isotope Labeling in Organic Synthesis: Acts as a key precursor for the synthesis of deuterium-labeled complex molecules, including pharmaceuticals and agrochemicals, for metabolic and pharmacokinetic studies.
• Pharmaceutical Research & Development: Employed in the development and analysis of deuterated drug candidates, where the deuterium label can alter metabolic profiles and improve drug stability.
• Biochemical Research: Utilized as a probe or tracer in studies of lipid peroxidation and related biochemical pathways involving malondialdehyde.
• Analytical Reference Material: Serves as a high-purity certified reference material (CRM) for quantitative analysis via GC-MS or LC-MS in analytical laboratories.
• Material Science Research: Used in the synthesis of specialized polymers or organic materials where isotopic labeling is required to study structure-property relationships.

Basic Information

Product Name	Malonaldehyde-1,3-D2 Bis(Diethyl Acetal)
CAS No.	105479-86-5
Molecular Formula	C11H22D2O4
Molecular Weight	218.32 g/mol (approx.)
Synonyms	1,1,3,3-Tetraethoxypropane-1,3-d2; Malondialdehyde Bis(diethyl acetal)-1,3-d2; Propanedial-1,3-d2, Bis(diethyl acetal); Deuterated Malonaldehyde Diethyl Acetal; MDA-d2 Bis(diethyl acetal); TEP-d2; 3-Oxopentanedial-1,3-d2 Bis(diethyl acetal); (1,1,3,3-Tetraethoxypropane-1,3-d2)
EINECS	Contact for details

Quality Control

Our Malonaldehyde-1,3-D2 Bis(Diethyl Acetal) is manufactured under strict quality control protocols to ensure high isotopic purity and chemical integrity, suitable for sensitive research applications. Each batch is analyzed using advanced techniques including NMR, GC-MS, and HPLC to confirm identity, chemical purity, and deuterium enrichment. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC)	≥ 98.0%
Deuterium Enrichment (NMR/MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.