Description

(1,2,3,4-Tetrahydro-Isoquinolin-1-Yl)-Acetic Acid is a high-purity organic building block of significant interest in advanced chemical synthesis. This compound serves as a critical intermediate for the development of novel pharmaceutical agents and bioactive molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for process development and active ingredient synthesis.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of potential therapeutic compounds, including central nervous system (CNS) agents and enzyme inhibitors.
• Agrochemical Synthesis: Used in the development of new pesticides and herbicides, leveraging its heterocyclic structure for biological activity.
• Fine Chemical Production: Serves as a versatile building block for creating complex molecules in custom synthesis and contract manufacturing.
• Academic & R&D: Employed in medicinal chemistry research for structure-activity relationship (SAR) studies and library synthesis.
• Chemical Reference Standard: Used as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	(1,2,3,4-Tetrahydro-Isoquinolin-1-Yl)-Acetic Acid
CAS No.	105400-81-5
Molecular Formula	C₁₁H₁₃NO₂
Molecular Weight	191.23 g/mol
Synonyms	1,2,3,4-Tetrahydro-1-isoquinolineacetic Acid; (1,2,3,4-Tetrahydroisoquinolin-1-yl)acetic Acid; 2-(1,2,3,4-Tetrahydroisoquinolin-1-yl)acetic Acid; 1-Carboxymethyl-1,2,3,4-tetrahydroisoquinoline; NSC 339586; Tetrahydroisoquinoline-1-acetic Acid; 1,2,3,4-Tetrahydro-isoquinoline-1-yl-acetic acid
EINECS	Contact for details

Quality Control

Our (1,2,3,4-Tetrahydro-Isoquinolin-1-Yl)-Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specification results. Our quality commitment ensures the material meets the stringent requirements for research and cGMP-grade pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.