Description

4-(Thien-3-Yl)-1,3-Thiazol-2-Amine CAS NO 105362-05-8 is a specialized heterocyclic organic compound featuring fused thiophene and thiazole rings with an amine functional group. This unique molecular architecture makes it a valuable pharmacophore and versatile building block in advanced chemical synthesis. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-infective therapies.
• Agrochemical Research: Serves as a core structure for developing new pesticides and herbicides with specific modes of action.
• Material Science: Used in the development of organic semiconductors, conductive polymers, and advanced electronic materials due to its electron-rich heterocyclic system.
• Ligand Synthesis: Acts as a chelating agent or ligand precursor in coordination chemistry and catalysis.
• Dye & Pigment Manufacturing: Employed as a building block for creating specialized chromophores and functional dyes.
• Academic & Contract Research: Essential for medicinal chemistry programs and structure-activity relationship (SAR) studies in university and CRO laboratories.

Basic Information

Product Name	4-(Thien-3-Yl)-1,3-Thiazol-2-Amine
CAS No.	105362-05-8
Molecular Formula	C7H6N2S2
Molecular Weight	182.27 g/mol
Synonyms	2-Amino-4-(3-thienyl)thiazole; 4-(3-Thienyl)-2-thiazolamine; 4-(Thiophen-3-yl)-1,3-thiazol-2-amine; 2-Thiazolamine, 4-(3-thienyl)-; 4-(3-Thienyl)thiazol-2-ylamine; 4-(Thiophen-3-yl)thiazol-2-amine; 105362-05-8
EINECS	Contact for details

Quality Control

Every batch of 4-(Thien-3-Yl)-1,3-Thiazol-2-Amine is produced under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.