Description

Thiophene, 2,5-Dihydro-2-(1-Methylethyl)-, 1,1-Dioxide (9Ci) is a specialized, high-purity sulfone derivative of thiophene, valued for its role as a versatile synthetic intermediate and building block in advanced organic synthesis. This compound matters for its ability to introduce specific steric and electronic properties into target molecules, enabling the development of novel materials and active pharmaceutical ingredients. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for creating complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, where the sulfone moiety can enhance biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Advanced Material Research: Employed in the development of organic semiconductors, conductive polymers, and other functional materials due to its electron-withdrawing sulfone group.
• Chemical Biology Probes: Utilized as a scaffold for designing molecular probes to study enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses serving the pharmaceutical and biotechnology industries.

Basic Information

Product Name	Thiophene, 2,5-Dihydro-2-(1-Methylethyl)-, 1,1-Dioxide (9Ci)
CAS No.	105230-91-9
Molecular Formula	C7H12O2S
Molecular Weight	160.23 g/mol
Synonyms	2-Isopropyl-2,5-dihydrothiophene 1,1-Dioxide; 2-(1-Methylethyl)-2,5-dihydrothiophene 1,1-Dioxide; 2,5-Dihydro-2-isopropylthiophene 1,1-Dioxide; 2-Isopropyl-2,5-dihydrothiophene Sulfone; 2-(Propan-2-yl)-2,5-dihydrothiophene 1,1-Dioxide
EINECS	Contact for details

Quality Control

Our Thiophene, 2,5-Dihydro-2-(1-Methylethyl)-, 1,1-Dioxide (9Ci) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support cGMP compliance for pharmaceutical applications and can provide material for regulatory filings upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.