Description

6H-Thieno(3,2-F)(1,2,4)Triazolo(4,3-A)(1,4)Diazepine-2-Propanamide, 4- (2-Chlorophenyl)-n-(2-Hydroxyethyl)-9-Methyl- is a high-purity, complex heterocyclic compound with significant pharmacological research interest. This compound matters as a key advanced intermediate or reference standard in the development of novel therapeutic agents targeting the central nervous system. Pharmaceutical R&D laboratories and fine chemical manufacturers require this material for its role in synthesizing and studying new chemical entities, particularly in the area of benzodiazepine-related analogs.

Application

• Pharmaceutical Research & Development (R&D): Serves as a critical intermediate in the synthesis of novel psychoactive pharmaceutical candidates.
• Reference Standard: Used as a high-purity analytical standard for method development, validation, and quality control in analytical laboratories.
• Medicinal Chemistry Studies: Employed in structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties.
• Preclinical Development: Utilized in the production of batches for pharmacological screening and toxicology assessments.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Used in university and institutional labs for fundamental research in neurochemistry and drug design.

Basic Information

Product Name	6H-Thieno(3,2-F)(1,2,4)Triazolo(4,3-A)(1,4)Diazepine-2-Propanamide, 4- (2-Chlorophenyl)-n-(2-Hydroxyethyl)-9-Methyl-
CAS No.	105219-71-4
Molecular Formula	C19H18ClN5O2S
Molecular Weight	415.89 g/mol
Synonyms	4-(2-Chlorophenyl)-N-(2-hydroxyethyl)-9-methyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-2-propanamide; Thienotriazolodiazepine Propanamide Derivative; 105219-71-4; 4-(2-Chlorophenyl)-9-methyl-N-(2-hydroxyethyl)-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-2-carboxamide (alternative naming); A thienotriazolodiazepine analog
EINECS	Contact for details

Quality Control

Our 6H-Thieno(3,2-F)(1,2,4)Triazolo(4,3-A)(1,4)Diazepine-2-Propanamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications and test results are provided to ensure traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%; Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.