Description

3-(3,5-Difluoro-Phenyl)-Propan-1-Ol is a valuable fluorinated aromatic alcohol building block, characterized by its propanol side chain and difluorophenyl moiety. This compound is essential for introducing specific fluorine-substituted aromatic motifs into target molecules, which can significantly alter their physicochemical and biological properties. It is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the difluorophenyl group enhances metabolic stability and bioavailability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs), improving performance and durability.
• Polymer & Resin Modifier: Incorporated as a monomer or additive to create specialty polymers with enhanced chemical resistance, thermal stability, and surface properties.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions, esterifications, and etherifications to construct complex molecular architectures in academic and industrial R&D.
• Flavor & Fragrance Chemistry: Acts as an intermediate for synthesizing novel aromatic compounds with specific olfactory profiles.

Basic Information

Item	Details
Product Name	3-(3,5-Difluoro-Phenyl)-Propan-1-Ol
CAS No.	105219-37-2
Molecular Formula	C9H10F2O
Molecular Weight	172.17 g/mol
Synonyms	3-(3,5-Difluorophenyl)-1-propanol; 3,5-Difluorophenylpropanol; 3,5-Difluorobenzene-1-propanol; 3-(3,5-Difluorophenyl)propan-1-ol; 1-Propanol, 3-(3,5-difluorophenyl)-; 3,5-Difluoro-β-hydroxypropylbenzene; 105219-37-2 (CAS)
EINECS	Contact for details

Quality Control

Our 3-(3,5-Difluoro-Phenyl)-Propan-1-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliable supply for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.