Description

(R)-A,2-Dimethyl-1H-Indole-1-Acetic Acid is a high-purity chiral indole derivative, a crucial building block in advanced organic synthesis. Its value lies in its role as a key intermediate for the development of active pharmaceutical ingredients (APIs) and other biologically active compounds. This product is essential for research and manufacturing in the pharmaceutical, agrochemical, and fine chemical industries, where precise stereochemistry is critical for efficacy.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and production of novel therapeutic agents, particularly in central nervous system (CNS) and anti-inflammatory drug discovery.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where specific stereoisomers exhibit enhanced biological activity.
• Asymmetric Catalysis Research: Serves as a valuable ligand precursor or substrate in the development of new catalytic systems for stereoselective reactions.
• Fine Chemical Manufacturing: Employed in the synthesis of complex, high-value specialty chemicals and flavors & fragrances.
• Academic & R&D: A critical reagent for universities and contract research organizations (CROs) exploring new synthetic methodologies and bio-active molecules.

Basic Information

Product Name	(R)-A,2-Dimethyl-1H-Indole-1-Acetic Acid
CAS No.	105119-82-2
Molecular Formula	C₁₂H₁₃NO₂
Molecular Weight	203.24 g/mol
Synonyms	(R)-1,2-Dimethylindole-3-acetic acid; (R)-α,2-Dimethyl-1H-indole-1-acetic acid; (R)-DMIA; (R)-1-(Carboxymethyl)-1,2-dimethylindole; (R)-1,2-Dimethyl-1H-indol-3-ylacetic acid; (+)-(R)-α,2-Dimethyl-1H-indole-1-acetic acid
EINECS	Contact for details

Quality Control

Our production of (R)-A,2-Dimethyl-1H-Indole-1-Acetic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chiral purity. Each lot is fully characterized and tested using advanced analytical techniques including HPLC, GC, and NMR. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral excess, and impurity profiles is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.