Description

Tibenelast (Sodium) CAS NO 105102-18-9 is a high-purity pharmaceutical intermediate and research chemical of significant interest in the development of novel therapeutic agents. This compound is valued for its role as a key building block in the synthesis of advanced pharmaceutical compounds, where consistent quality and reliable supply are paramount. It is primarily utilized by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers engaged in the creation of new drug candidates and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard or experimental compound in pharmacological and biochemical studies to investigate biological pathways.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.
• Academic Research: Employed in university and institutional labs for medicinal chemistry projects and the development of new synthetic methodologies.
• Process Development: Serves as a key material for scaling up and optimizing synthetic routes in process chemistry.

Basic Information

Product Name	Tibenelast (Sodium)
CAS No.	105102-18-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Tibenelast Sodium; Sodium Tibenelast; 105102-18-9; Tibenelast Na; 1,3-Dihydro-3-(1H-imidazol-1-ylmethyl)-5-phenyl-2H-1,4-benzodiazepin-2-one sodium salt; 3-(Imidazol-1-ylmethyl)-5-phenyl-1,4-benzodiazepin-2-one sodium salt
EINECS	Contact for details

Quality Control

Our Tibenelast (Sodium) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as identity, assay, and impurity profiles. We support development and commercial projects with material suitable for research use and can provide grades aligned with cGMP standards for advanced pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.