Description

2-Aminobenzoic Acid, [Ring-14C(U)] is a carbon-14 labeled isotopologue of anthranilic acid, a key aromatic amino acid derivative. This radiolabeled compound is essential for conducting precise metabolic and pharmacokinetic studies, enabling researchers to trace the compound's pathway and fate within biological systems. It is a critical tool for scientists in the pharmaceutical, agrochemical, and life science research sectors who require high-specific-activity tracers for advanced analytical applications.

Application

• Drug Metabolism and Pharmacokinetics (DMPK) Studies: Used as a radiotracer to investigate the absorption, distribution, metabolism, and excretion (ADME) of pharmaceutical compounds and their metabolites.
• Environmental Fate Studies: Employed in agrochemical research to trace the degradation pathways, soil mobility, and bioaccumulation of chemical agents.
• Biochemical Pathway Analysis: Serves as a labeled precursor or intermediate for studying biosynthetic routes and enzymatic mechanisms in vivo and in vitro.
• Analytical Method Development: Acts as an internal standard or reference material in Liquid Chromatography-Mass Spectrometry (LC-MS) and other chromatographic techniques for quantitative analysis.
• Medical Research: Utilized in tracer studies related to tryptophan metabolism and its role in various physiological and pathological processes.

Basic Information

Product Name	2-Aminobenzoic Acid, [Ring-14C(U)]
CAS No.	104809-47-4
Molecular Formula	C7H714CNO2
Molecular Weight	~138.1 (based on 12C formula C7H7NO2)
Synonyms	Anthranilic Acid-[ring-14C(U)]; [Ring-U-14C]Anthranilic Acid; 2-Amino[14C]benzoic Acid; o-Aminobenzoic Acid-14C; Carbon-14 Labeled Anthranilic Acid; Vitamin L1 (labeled); Benzoc Acid, 2-amino-, [14C]
EINECS	Contact for details

Quality Control

Every batch of our 2-Aminobenzoic Acid, [Ring-14C(U)] is manufactured and analyzed under strict quality control protocols to ensure the highest standards of radiochemical purity and specific activity. Our products undergo rigorous quality testing, including HPLC and radio-HPLC analysis, to ensure compliance with industry standards for radiolabeled compounds. Certificates of Analysis (COA) detailing specific activity, radiochemical purity, chemical purity, and analytical methods are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at recommended temperatures (typically 2-8°C or as specified on the label) to maintain stability. Store in accordance with all local, national, and international regulations governing radioactive materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Specific Activity	Customizable (mCi/mmol)
Radiochemical Purity (HPLC)	≥ 95%
Chemical Purity (HPLC)	≥ 98%
Solvent (for solutions)	Specified on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.