Description

Methyl-13C-D3-Amine Hydrochloride is a stable isotope-labeled compound of significant importance in analytical chemistry and life sciences research. This high-purity material serves as a critical internal standard and tracer, enabling precise quantification and metabolic pathway elucidation. It is essential for researchers and quality control laboratories in the pharmaceutical, agrochemical, and environmental analysis sectors who require uncompromising isotopic purity and chemical stability for advanced mass spectrometry (MS) and nuclear magnetic resonance (NMR) applications.

Application

• Internal Standard for Quantitative Analysis by LC-MS/MS and GC-MS in pharmaceutical bioanalysis and pharmacokinetic studies.
• Metabolic Pathway Tracer and Probe in drug metabolism and disposition (DMPK) research using stable isotope labeling.
• Chemical Reference Standard for the calibration and validation of analytical methods in regulatory environments (e.g., FDA, EMA submissions).
• Precursor in the synthesis of more complex carbon-13 (13C) and deuterium (D) labeled compounds for use as probes.
• Substrate for enzymatic and biochemical studies where tracking of methyl group transfer is required.
• Component in environmental fate studies to trace the degradation and transformation of amine-containing compounds.

Basic Information

Product Name	Methyl-13C-D3-Amine Hydrochloride
CAS No.	104809-19-0
Molecular Formula	13CH3D3N•HCl
Molecular Weight	55.54 g/mol
Synonyms	Methylamine-13C,d3 hydrochloride; (13C)Methyl-d3-amine hydrochloride; Methylamine-13C,N-d3 hydrochloride; Deuterated Methyl-13C-amine HCl; 13C,D3-Labeled Methylamine Hydrochloride; Aminomethane-13C,d3 hydrochloride; Monomethylamine-13C,d3 hydrochloride
EINECS	Contact for details

Quality Control

Every batch of Methyl-13C-D3-Amine Hydrochloride is produced and tested under a strict quality management system. We guarantee high chemical and isotopic purity, with comprehensive testing including assay, isotopic enrichment (by NMR and MS), and impurity profiling. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting compliance with customer specifications and relevant industry standards for advanced research materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and must be handled under inert atmosphere (argon or nitrogen) when opening to prevent degradation. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Isotopic Enrichment (13C)	≥ 99 atom %
Isotopic Enrichment (D)	≥ 98 atom % (D3)
Chemical Purity (NMR)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.