Description

Methyl 2-Oxo-2-(Thiophen-3-Yl)Acetate is a high-purity organic building block and synthetic intermediate of significant commercial interest. This compound is valued for its reactive α-ketoester functionality adjacent to a thiophene heterocycle, enabling its use in the synthesis of complex molecules. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of thiophene-containing drug candidates, particularly in central nervous system (CNS) and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the thiophene moiety imparts specific biological activity.
• Material Science Research: Serves as a monomer or functional unit in the development of conductive polymers, organic semiconductors, and non-linear optical (NLO) materials.
• Chemical Biology Probes: Employed in the design and synthesis of enzyme inhibitors, receptor ligands, and fluorescent tags for biochemical research.
• Fine Chemical Production: Acts as a versatile building block for custom synthesis and contract manufacturing of specialty chemicals.

Basic Information

Product Name	Methyl 2-Oxo-2-(Thiophen-3-Yl)Acetate
CAS No.	104749-67-9
Molecular Formula	C7H6O3S
Molecular Weight	170.19 g/mol
Synonyms	Methyl 2-oxo-2-(3-thienyl)acetate; 2-Oxo-2-(thiophen-3-yl)acetic acid methyl ester; 3-Thiopheneglyoxylic acid methyl ester; Methyl 3-thienylglyoxylate; Methyl (3-thienyl)oxoacetate; 3-Thienylglyoxylic acid methyl ester; Methyl α-oxo-3-thiopheneacetate
EINECS	Contact for details

Quality Control

Our production of Methyl 2-Oxo-2-(Thiophen-3-Yl)Acetate adheres to stringent quality management protocols. Every batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and IR spectroscopy to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.