Description

8-Fluoro-1,2,3,4-Tetrahydro-1-((3,4,5-Trimethoxyphenyl)Methyl)-6,7-Iso Quinolinediol is a sophisticated synthetic intermediate of significant interest in advanced organic synthesis. This compound matters for its role as a key building block in the development of complex pharmacologically active molecules, particularly within the isoquinoline alkaloid class. Pharmaceutical R&D and fine chemical synthesis laboratories need this high-purity material to support the discovery and process development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel isoquinoline-based drug candidates targeting central nervous system (CNS) disorders.
• Research & Development: Used in academic and industrial research for studying structure-activity relationships (SAR) and developing new synthetic methodologies.
• Fine Chemical Synthesis: Serves as a versatile building block for constructing complex heterocyclic compounds with potential biological activity.
• Reference Standard: Employed as an analytical standard for quality control and method validation in pharmaceutical manufacturing.
• Biochemical Tool Compound: Utilized in pharmacological studies to investigate enzyme inhibition or receptor binding mechanisms.
• Process Chemistry: Integral to scaling up synthetic routes for potential Active Pharmaceutical Ingredients (APIs) under Good Manufacturing Practice (GMP) conditions.

Basic Information

Item	Detail
Product Name	8-Fluoro-1,2,3,4-Tetrahydro-1-((3,4,5-Trimethoxyphenyl)Methyl)-6,7-Iso Quinolinediol
CAS No.	104716-89-4
Molecular Formula	C20H22FNO5
Molecular Weight	375.39 g/mol
Synonyms	8-Fluoro-1,2,3,4-tetrahydro-1-[(3,4,5-trimethoxyphenyl)methyl]-6,7-isoquinolinediol; 1-[(3,4,5-Trimethoxyphenyl)methyl]-8-fluoro-1,2,3,4-tetrahydro-6,7-isoquinolinediol; 8-Fluoro-1-[(3,4,5-trimethoxybenzyl)]-1,2,3,4-tetrahydro-6,7-dihydroxyisoquinoline; 104716-89-4; Fluorinated tetrahydroisoquinoline derivative; Trimethoxyphenylmethyl isoquinolinediol
EINECS	Contact for details

Quality Control

Our 8-Fluoro-1,2,3,4-Tetrahydro-1-((3,4,5-Trimethoxyphenyl)Methyl)-6,7-Iso Quinolinediol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. All products undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.