Description

4-Bromo-1-Methyl-Isoquinoline is a versatile brominated isoquinoline derivative, a crucial building block in advanced organic synthesis. Its value lies in its role as a key intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and material science. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity intermediates for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a core scaffold for the synthesis of potential drug candidates, including kinase inhibitors and other biologically active molecules.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging the isoquinoline structure's bioactivity.
• Material Science Precursor: Acts as a building block for creating organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce the 1-methylisoquinoline moiety into more complex systems.
• Ligand Synthesis: Useful for preparing specialized ligands used in catalysis and coordination chemistry.
• Academic & R&D: A valuable reagent for methodological studies and exploring new synthetic pathways in university and industrial research laboratories.

Basic Information

Item	Detail
Product Name	4-Bromo-1-Methyl-Isoquinoline
CAS No.	104704-40-7
Molecular Formula	C₁₀H₈BrN
Molecular Weight	222.08 g/mol
Synonyms	1-Methyl-4-bromoisoquinoline; 4-Bromo-1-methylisoquinoline; 4-Bromo-1-methyl-isoquinoline; Isoquinoline, 4-bromo-1-methyl-; 1-Methylisoquinoline, 4-bromo derivative
EINECS	Contact for details

Quality Control

Our 4-Bromo-1-Methyl-Isoquinoline is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request, providing full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.