Description

(S)-(-)-2-Hydroxy-n-Methylsuccinimide is a high-purity chiral succinimide derivative, a key building block in asymmetric synthesis. This compound is valued for its role as a versatile intermediate in the production of optically active pharmaceuticals and advanced materials. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for developing novel active ingredients and chiral catalysts.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in neurologic and metabolic drug research.
• Asymmetric Catalyst Ligand Precursor: Used in the development and synthesis of chiral ligands for metal-catalyzed asymmetric reactions.
• Agrochemical Synthesis: Serves as a building block for creating enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring high stereochemical purity.
• Academic & Industrial R&D: A valuable reference standard and starting material in methodological development for organic and medicinal chemistry.
• Polymer Modification: Can be utilized to introduce chiral centers or functional groups into polymer backbones for advanced material properties.

Basic Information

Product Name	(S)-(-)-2-Hydroxy-n-Methylsuccinimide
CAS No.	104612-35-3
Molecular Formula	C5H7NO3
Molecular Weight	129.11 g/mol
Synonyms	(S)-2-Hydroxy-1-methylpyrrolidine-2,5-dione; (S)-(-)-1-Methyl-2-hydroxysuccinimide; (S)-2-Hydroxy-N-methylsuccinimide; (S)-1-Methyl-2-hydroxypyrrolidine-2,5-dione; (2S)-2-Hydroxy-1-methyl-5-oxopyrrolidine-3-carboxylic acid lactam; (S)-2-Hydroxy-1-methyl-2,5-pyrrolidinedione
EINECS	Contact for details

Quality Control

Our (S)-(-)-2-Hydroxy-n-Methylsuccinimide is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for synthetic applications. A Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.