Description

2,3,4,9-Tetrahydro-1H-β-Carboline-4-Carboxylic Acid Methyl Ester is a significant heterocyclic building block and key synthetic intermediate in organic chemistry. This compound matters for its role as a versatile precursor in the synthesis of complex alkaloids and pharmacologically active molecules, offering a rigid scaffold for drug discovery. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of central nervous system (CNS) agents and other therapeutic compounds. The product is supplied with a high level of purity and batch-to-batch consistency to support critical R&D and scale-up processes.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of β-carboline alkaloids and related derivatives with potential biological activity.
• Medicinal Chemistry Research: Used as a core scaffold for designing and developing novel drug candidates targeting neurological disorders.
• Organic Synthesis Building Block: Employed in complex multi-step syntheses to construct polycyclic frameworks due to its fused ring system.
• Biochemical Research: Serves as a reference standard or starting material for studying enzyme inhibitors and receptor ligands.
• Academic Research: Utilized in university and institutional labs for methodological studies and the exploration of new synthetic pathways.

Basic Information

Product Name	2,3,4,9-Tetrahydro-1H-β-Carboline-4-Carboxylic Acid Methyl Ester
CAS No.	104580-74-7
Molecular Formula	C₁₃H₁₄N₂O₂
Molecular Weight	230.26 g/mol
Synonyms	1,2,3,4-Tetrahydro-9H-pyrido[3,4-b]indole-3-carboxylic acid methyl ester; Methyl 1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole-3-carboxylate; Tetrahydro-β-carboline-3-carboxylic acid methyl ester; 3-Carbomethoxy-1,2,3,4-tetrahydro-β-carboline; 3-Methoxycarbonyl-1,2,3,4-tetrahydro-β-carboline; β-Carboline-3-carboxylic acid methyl ester, tetrahydro-; 3-(Methoxycarbonyl)-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole
EINECS	Contact for details

Quality Control

Our 2,3,4,9-Tetrahydro-1H-β-Carboline-4-Carboxylic Acid Methyl Ester is manufactured under controlled conditions to ensure high purity and reliability. Each batch undergoes rigorous analytical testing, including HPLC for assay and purity determination, to meet stringent in-house specifications. A comprehensive Certificate of Analysis (COA) documenting identity, purity, and related substances is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.