Description

(12As)-2,3,12,12A-Tetrahydro1-Methyl-6,9-Dimethoxy-1H-[1]Benzooxepino[2,3,4-Ij]Isoquinoline-10-Ol is a complex heterocyclic compound belonging to the isoquinoline alkaloid class, valued for its intricate molecular architecture. This compound is a critical advanced pharmaceutical intermediate and a valuable scaffold in medicinal chemistry research for developing novel therapeutic agents. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of high-potency active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex alkaloid-based active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Core scaffold for structure-activity relationship (SAR) studies and the development of new drug candidates targeting neurological and other disorders.
• Biochemical Research: Used as a reference standard or probe in pharmacological studies to investigate receptor interactions and biological pathways.
• Fine Chemical Synthesis: Serves as a precursor for the preparation of more complex, functionalized isoquinoline derivatives.
• Academic Research: Utilized in university and institutional labs for synthetic organic chemistry studies and methodology development.

Basic Information

Item	Detail
Product Name	(12As)-2,3,12,12A-Tetrahydro1-Methyl-6,9-Dimethoxy-1H-[1]Benzooxepino[2,3,4-Ij]Isoquinoline-10-Ol
CAS No.	104420-84-0
Molecular Formula	C₂₁H₂₁NO₄
Molecular Weight	351.40 g/mol
Synonyms	1H-[1]Benzoxepino[2,3,4-ij]isoquinoline-10-ol, 2,3,12,12a-tetrahydro-1-methyl-6,9-dimethoxy-, (12aS)-; (12aS)-2,3,12,12a-Tetrahydro-1-methyl-6,9-dimethoxy-1H-[1]benzoxepino[2,3,4-ij]isoquinolin-10-ol; NSC 339587; Aporphine alkaloid derivative; Isoquinoline benzoxepine derivative; Tetrahydroprotoberberine analog.
EINECS	Contact for details

Quality Control

Our (12As)-2,3,12,12A-Tetrahydro1-Methyl-6,9-Dimethoxy-1H-[1]Benzooxepino[2,3,4-Ij]Isoquinoline-10-Ol is produced under strict quality management systems suitable for research and development applications. All batches undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.