Description

Methyl 4-Chloro-3-Hydroxy-5-(Methylthio)Thiophene-2-Carboxylate is a high-purity, functionalized thiophene derivative serving as a critical advanced intermediate in organic synthesis. Its value lies in its unique molecular scaffold, which combines halogen, hydroxyl, and thioether functionalities, making it a versatile building block for constructing complex heterocyclic systems. This compound is essential for R&D chemists and process development scientists in the pharmaceutical and agrochemical industries seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in developing molecules with thiophene-based cores for various therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, where the thiophene moiety can contribute to biological activity.
• Material Science Research: Serves as a precursor for functionalized polymers, organic semiconductors, and conductive materials due to the electron-rich thiophene structure.
• Organic Synthesis Reagent: A versatile synthon for constructing complex heterocycles via further functionalization of the chloro, hydroxy, and ester groups.
• Chemical Research & Development: Fundamental compound for method development and exploring new chemical reactions in academic and industrial laboratories.

Basic Information

Product Name	Methyl 4-Chloro-3-Hydroxy-5-(Methylthio)Thiophene-2-Carboxylate
CAS No.	104386-68-7
Molecular Formula	C8H7ClO3S2
Molecular Weight	250.72 g/mol
Synonyms	Methyl 4-chloro-3-hydroxy-5-(methylthio)thiophene-2-carboxylate; 4-Chloro-3-hydroxy-5-(methylthio)thiophene-2-carboxylic acid methyl ester; 2-Thiophenecarboxylic acid, 4-chloro-3-hydroxy-5-(methylthio)-, methyl ester; Methyl 4-chloro-3-hydroxy-5-methylsulfanylthiophene-2-carboxylate; 104386-68-7; Thiophene-2-carboxylic acid, 4-chloro-3-hydroxy-5-(methylthio)-, methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 4-Chloro-3-Hydroxy-5-(Methylthio)Thiophene-2-Carboxylate adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. Every lot is fully characterized and analyzed using advanced techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment, ensuring full traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.