Description

2-Mercaptomethyl-Pyrrolidine-1-Carboxylic Acid Benzyl Ester CAS NO 104379-90-0 is a versatile chiral building block and intermediate in organic synthesis, characterized by its pyrrolidine scaffold and protected thiol and carboxylic acid functionalities. This compound is crucial for the development of complex molecules, particularly in pharmaceutical research where it serves as a key precursor for active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by R&D laboratories, process chemists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of protease inhibitors, enzyme inhibitors, and other biologically active molecules.
• Peptidomimetics Research: Used to construct constrained peptide analogs and peptidomimetic scaffolds due to its pyrrolidine ring structure.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts in asymmetric synthesis.
• Custom Synthesis Building Block: Employed in contract research and manufacturing (CRO/CMO) for the custom synthesis of complex organic targets.
• Agrochemical Active Ingredient Synthesis: Intermediate in the production of advanced crop protection agents.
• Chemical Biology Probes: Useful for creating probes and tool compounds for studying biological pathways.

Basic Information

Product Name	2-Mercaptomethyl-Pyrrolidine-1-Carboxylic Acid Benzyl Ester
CAS No.	104379-90-0
Molecular Formula	C14H19NO2S
Molecular Weight	265.37 g/mol
Synonyms	1-[(Benzyloxy)carbonyl]-2-(mercaptomethyl)pyrrolidine; Benzyl 2-(mercaptomethyl)pyrrolidine-1-carboxylate; 2-(Mercaptomethyl)-1-pyrrolidinecarboxylic Acid Phenylmethyl Ester; 1-CBZ-2-Mercaptomethylpyrrolidine; (2-Mercaptomethyl-1-pyrrolidinyl)-carboxylic Acid Benzyl Ester; 1-N-CBZ-2-Mercaptomethylpyrrolidine; 2-Mercaptomethyl-1-pyrrolidinecarboxylic Acid Benzyl Ester
EINECS	Contact for details

Quality Control

Our 2-Mercaptomethyl-Pyrrolidine-1-Carboxylic Acid Benzyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. This compound is easily oxidized and light-sensitive. Allow the container to reach ambient temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.