Description

3-(4-Fluoro-Phenyl)-2-Thiophen-2-Yl-Acrylic Acid is a high-purity fluorinated heterocyclic building block essential for advanced organic synthesis. This compound is valued for its unique molecular architecture, which combines a fluorinated phenyl ring with a thiophene-acrylic acid moiety, making it a versatile intermediate in the development of novel active compounds. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for creating new molecules with targeted properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for anti-inflammatory, antiviral, or CNS-targeted therapies.
• Agrochemical Research: Used in developing new active ingredients for crop protection products, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialty polymers and advanced organic electronic materials.
• Chemical Synthesis Building Block: Employed in cross-coupling reactions, such as Suzuki or Heck reactions, to construct complex molecular frameworks in academic and industrial R&D.
• Ligand and Catalyst Development: Utilized for designing novel ligands in coordination chemistry and catalysis due to its electron-rich thiophene and coordinating carboxylic acid group.

Basic Information

Product Name	3-(4-Fluoro-Phenyl)-2-Thiophen-2-Yl-Acrylic Acid
CAS No.	104314-04-7
Molecular Formula	C₁₃H₉FO₂S
Molecular Weight	248.27 g/mol
Synonyms	3-(4-Fluorophenyl)-2-(thiophen-2-yl)acrylic acid; 2-(2-Thienyl)-3-(4-fluorophenyl)propenoic Acid; (E)-3-(4-Fluorophenyl)-2-(thiophen-2-yl)acrylic Acid; 3-(p-Fluorophenyl)-2-(2-thienyl)acrylic Acid; 104314-04-7; 3-(4-Fluoro-Phenyl)-2-Thiophen-2-Yl-Acrylic Acid; 3-(4-Fluorophenyl)-2-(2-thienyl)acrylic acid; 2-(Thiophen-2-yl)-3-(4-fluorophenyl)acrylic acid
EINECS	Contact for details

Quality Control

Our 3-(4-Fluoro-Phenyl)-2-Thiophen-2-Yl-Acrylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for research and regulated product development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.