Description

Ethyl 6-Cyano-1H-Indole-2-Carboxylate is a high-purity, versatile indole derivative serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both ester and nitrile functional groups, makes it an essential precursor for constructing complex heterocyclic compounds. This intermediate is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex indole-based drug candidates, particularly for kinase inhibitors and receptor modulators.
• Agrochemical Research: Used in developing novel herbicides and plant growth regulators that leverage the indole scaffold.
• Material Science: Serves as a precursor for functional organic materials, including dyes, pigments, and organic semiconductors.
• Academic & Contract Research: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies and library synthesis.
• Chemical Biology: Utilized as a probe or labeling agent due to its reactive functional groups.

Basic Information

Item	Details
Product Name	Ethyl 6-Cyano-1H-Indole-2-Carboxylate
CAS No.	104291-81-8
Molecular Formula	C12H10N2O2
Molecular Weight	214.22 g/mol
Synonyms	6-Cyano-1H-indole-2-carboxylic acid ethyl ester; Ethyl 6-cyanoindole-2-carboxylate; 2-Carbethoxy-6-cyanoindole; 1H-Indole-2-carboxylic acid, 6-cyano-, ethyl ester; 6-CN-1H-Indole-2-COOEt; Ethyl 2-carboxy-6-cyanoindole; 104291-81-8
EINECS	Contact for details

Quality Control

Our Ethyl 6-Cyano-1H-Indole-2-Carboxylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.