Description

Methyl Glycyrrhizate is a methyl ester derivative of glycyrrhizic acid, a key bioactive compound from licorice root. This refined ingredient offers enhanced solubility and stability, making it a valuable asset for formulators seeking consistent performance. It is primarily utilized in the personal care, cosmetics, and pharmaceutical industries as a high-potency skin conditioning agent and flavor modifier. Its commercial significance lies in delivering reliable, standardized bioactivity for advanced formulations.

Application

• Cosmetic & Skincare Formulations: Used as a potent skin conditioning, soothing, and anti-irritant agent in creams, lotions, serums, and after-sun products.
• Pharmaceutical Preparations: Employed in topical formulations for its anti-inflammatory and demulcent properties, and as a flavoring agent in oral syrups and lozenges.
• Oral Care Products: Incorporated into toothpaste and mouthwash for its sweetening and soothing effects on oral mucosa.
• Functional Food & Beverages: Serves as a high-intensity natural sweetener and flavor enhancer in specialized dietary products.
• Hair Care Products: Added to shampoos and conditioners for its scalp-soothing and anti-dandruff potential.
• Advanced Dermatological Research: Used as a reference standard or active ingredient in studies focused on skin barrier function and inflammation.

Basic Information

Product Name	Methyl Glycyrrhizate
CAS No.	104191-95-9
Molecular Formula	C₄₃H₆₄O₁₆
Molecular Weight	837.0 g/mol
Synonyms	Methyl Glycyrrhizinate; Glycyrrhizic Acid Methyl Ester; Methyl 20β-Carboxy-11-oxo-30-norolean-12-en-3β-yl-2-O-β-D-glucopyranuronosyl-α-D-glucopyranosiduronate; Enoxolone Methyl Ester; Licorice Saponin G2 Methyl Ester; MG; Methyl Glycyrrhetate Glucuronosyl Glucuronide
EINECS	Contact for details

Quality Control

Our Methyl Glycyrrhizate is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Quality is verified through comprehensive analytical testing, including HPLC for assay and related substances. A Certificate of Analysis (COA) detailing identity, purity, and specific tests is provided with each shipment. We support compliance with relevant standards for cosmetic and pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed after opening to prevent absorption of atmospheric moisture, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 95.0%
Loss on Drying	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm
Microbiological Control	Meets standard limits for cosmetic ingredients

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.