Description

cis-Isohumulone is a key isomer of isohumulone, a primary bittering component derived from hops. This compound is essential for imparting and modulating the characteristic bitter flavor profile in beer and other hop-derived products. It is a critical ingredient for breweries, flavor houses, and research institutions focused on beverage formulation, quality control, and sensory science. Its precise chemical structure allows for targeted flavor adjustment and stability studies in final products.

Application

• Brewing Industry: As a reference standard and direct additive for precise bitterness calibration and flavor profiling in beer production.
• Flavor & Fragrance: A key component in creating and standardizing bitter flavorants for beverages and food products.
• Quality Control & Analytical Laboratories: Used as a high-purity analytical standard for HPLC, GC-MS, and spectrophotometric methods to quantify hop bitter acids in raw materials and finished beers.
• Research & Development: Fundamental for studies on beer flavor stability, antioxidant properties, and the chemical transformations of hop compounds during brewing and storage.
• Sensory Science: Employed in taste panel training and the development of standardized bitterness scales.

Basic Information

Product Name	cis-Isohumulone
CAS No.	1534-03-8
Molecular Formula	C21H30O5
Molecular Weight	362.46 g/mol
Synonyms	(2E)-3,5,6-Trihydroxy-4-(3-methylbut-2-en-1-yl)-2-[(3-methylbutanoyl)oxy]hex-2-enoic acid; (Z)-Isohumulone; Isohumulone A; Iso-α-acid; cis-Iso-α-acid; trans-Isohumulone (related isomer); Colupulone derivative
EINECS	Contact for details

Quality Control

Our cis-Isohumulone is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for analytical and research applications. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and degradation. The container should be kept in a cool, dry, and well-ventilated area.

Specification

Item	Specification
Appearance	Yellow to amber powder or resin
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0% (cis-Isohumulone)
Related Substances (HPLC)	Total impurities ≤ 5.0%
Solvent Residues (GC)	Meets ICH guidelines
Water Content (KF)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.