Description

6″-o-Acetylsaikosaponin B3 is a specific, acetylated derivative of the bioactive saikosaponin B3, a key triterpenoid saponin found in medicinal plants like *Bupleurum* species. This compound is of significant interest for its enhanced pharmacological profile and serves as a critical reference standard and intermediate in pharmaceutical research and development. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and nutraceutical industries for drug discovery, quality control of herbal extracts, and metabolic studies.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of saikosaponin derivatives in raw materials, herbal extracts, and finished products via HPLC, LC-MS, or TLC.
• Biochemical Research: Serves as a key intermediate or probe in studying the structure-activity relationships (SAR) of saikosaponins, their anti-inflammatory, hepatoprotective, and antiviral mechanisms.
• Drug Discovery & Development: Acts as a precursor or lead compound for the semi-synthesis of novel derivatives with optimized bioavailability and therapeutic efficacy.
• Nutraceutical Quality Control: Employed to standardize and authenticate high-value *Bupleurum*-based dietary supplements and traditional medicine formulations.
• Academic Research: Utilized in university and institutional labs for pharmacological, phytochemical, and metabolic pathway investigations.

Basic Information

Product Name	6″-o-Acetylsaikosaponin B3
CAS No.	104109-34-4
Molecular Formula	C48H78O17
Molecular Weight	927.1 g/mol
Synonyms	6''-O-Acetylsaikosaponin B3; Acetyl Saikosaponin B3; Saikosaponin B3 6''-acetate; (3β,4α,16β)-13,28-Epoxy-16,23-dihydroxyolean-11-en-3-yl 6-O-acetyl-β-D-glucopyranosyl-(1→2)-β-D-glucopyranosyl-(1→3)-β-D-fucopyranoside
EINECS	Contact for details

Quality Control

Every batch of 6″-o-Acetylsaikosaponin B3 is produced and analyzed under strict quality management protocols. Our products undergo rigorous identity, purity, and impurity profile testing using advanced analytical techniques to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, chromatographic data, and spectroscopic identification is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95.0%
Loss on Drying	≤2.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.