Description

3-(Trifluoromethyl)Pyridine-2-Thiol is a high-value organofluorine and heterocyclic building block. This compound is essential for introducing the trifluoromethylthio-pyridine moiety into complex molecular architectures, significantly altering physicochemical properties. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for developing active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides where the trifluoromethyl group enhances bioavailability and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic materials with tailored electronic properties.
• Chemical Biology Probes: Utilized in the design of molecular probes and inhibitors for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	3-(Trifluoromethyl)Pyridine-2-Thiol
CAS No.	104040-74-6
Molecular Formula	C6H4F3NS
Molecular Weight	179.16 g/mol
Synonyms	2-Mercapto-3-(trifluoromethyl)pyridine; 3-(Trifluoromethyl)-2-pyridinethiol; 2-Pyridinethiol, 3-(trifluoromethyl)-; 3-Trifluoromethylpyridine-2-thiol; 2-Thiol-3-trifluoromethylpyridine; 3-TFM-Py-2-SH
EINECS	Contact for details

Quality Control

Our 3-(Trifluoromethyl)Pyridine-2-Thiol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.