Description

Ceftiofur Hydrochloride is a third-generation cephalosporin antibiotic specifically designed for veterinary use. Its primary value lies in its broad-spectrum activity against Gram-positive and Gram-negative bacteria, making it a critical tool for managing respiratory and other systemic infections in livestock. This product is essential for manufacturers in the veterinary pharmaceutical industry producing injectable solutions, as well as for animal health research and development.

Application

• Veterinary Pharmaceutical Formulations: Primary active ingredient in sterile injectable solutions for the treatment of bacterial infections in cattle, swine, and poultry.
• Respiratory Disease Management: Specifically indicated for the treatment of bovine respiratory disease (BRD) and swine respiratory disease.
• Metritis and Mastitis Control: Used in the treatment of postpartum metritis in dairy cows and mastitis in cattle.
• Pododermatitis Treatment: Applied in protocols for treating infectious pododermatitis (foot rot) in cattle.
• Animal Health Research: Serves as a reference standard and active component in preclinical and clinical studies for new veterinary therapeutics.
• Feed Additive Precursor: Used in the development of medicated feed premixes, subject to regional regulatory approvals.

Basic Information

Product Name	Ceftiofur Hydrochloride
CAS No.	103980-44-5
Molecular Formula	C19H17N5O7S3·HCl
Molecular Weight	560.0 g/mol (as free base)
Synonyms	Ceftiofur HCl; (6R,7R)-7-[[(2Z)-2-(2-Amino-4-thiazolyl)-2-methoxyiminoacetyl]amino]-3-[[(2-furanylcarbonyl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hydrochloride; U-64279A; U-64279E; Excenel; Excede; Naxcel; Cefenil; Veterinary Cephalosporin
EINECS	Contact for details

Quality Control

Our Ceftiofur Hydrochloride is manufactured and tested to meet high-purity standards suitable for veterinary pharmaceutical applications. Each batch undergoes rigorous analytical testing including HPLC for assay and related substances, identification by IR and HPLC comparison, and tests for residual solvents and heavy metals. A comprehensive Certificate of Analysis (COA) documenting compliance with in-house specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. The container should be kept tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
pH (1% Solution)	3.0 - 5.0
Specific Optical Rotation	+55° to +65° (c=1, in water)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.