Description

Methyl 3-(4-Nitrophenoxy)-2-thiophenecarboxylate is a high-purity, specialized organic building block featuring a thiophene core functionalized with a nitrophenoxy group. This compound is valued for its role as a critical synthetic intermediate in advanced pharmaceutical and agrochemical research and development. It is primarily sought by R&D chemists and process development scientists in the fine chemical and life sciences industries for constructing complex molecules with potential biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders or possessing specific receptor modulation activity.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, where the thiophene and nitrophenoxy motifs can contribute to biological efficacy.
• Material Science: Serves as a monomer or functionalizing agent in the research of conductive polymers or organic semiconductors due to the electron-rich thiophene unit.
• Dye & Pigment Synthesis: Acts as an intermediate for creating specialized dyes and organic pigments, leveraging its aromatic structure and nitro group for color development.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in heterocyclic and cross-coupling chemistry.
• Custom Synthesis: A starting point for the contract manufacturing of proprietary compounds for clients in various high-tech chemical sectors.

Basic Information

Product Name	Methyl 3-(4-Nitrophenoxy)-2-thiophenecarboxylate
CAS No.	103790-37-0
Molecular Formula	C12H9NO5S
Molecular Weight	279.27 g/mol
Synonyms	Methyl 3-(4-nitrophenoxy)thiophene-2-carboxylate; 2-Thiophenecarboxylic acid, 3-(4-nitrophenoxy)-, methyl ester; 3-(p-Nitrophenoxy)-2-thiophenecarboxylic acid methyl ester; Methyl 3-(p-nitrophenoxy)thiophene-2-carboxylate; 3-(4-Nitrophenoxy)thiophene-2-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Every batch of Methyl 3-(4-Nitrophenoxy)-2-thiophenecarboxylate is manufactured under strict quality management protocols. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles to ensure compliance with your research or production specifications. Our rigorous analytical testing, including HPLC, GC, and NMR, guarantees batch-to-batch consistency and reliable performance in your synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.