Description

1,2,3,4-Tetrahydro-6,7-Dimethoxy-3-Isoquinolinecarboxylic Acid Phenylmethyl Ester Hydrochloride is a high-purity synthetic intermediate of significant importance in advanced organic synthesis. This compound is valued for its role as a key building block in the development of complex pharmaceutical molecules, particularly those targeting neurological pathways. It is primarily required by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers engaged in the synthesis of novel therapeutic agents and reference standards.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potent alkaloid-derived active pharmaceutical ingredients (APIs).
• Neurological Research: Serves as a key scaffold for developing compounds for neuroscience research, including potential dopaminergic or adrenergic agents.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization processes for new drug candidates.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Process Chemistry: Employed in scale-up and route development for the commercial manufacturing of specialty fine chemicals.
• Academic Research: Utilized in university and institutional labs for synthetic methodology development and heterocyclic chemistry studies.

Basic Information

Product Name	1,2,3,4-Tetrahydro-6,7-Dimethoxy-3-Isoquinolinecarboxylic Acid Phenylmethyl Ester Hydrochloride
CAS No.	103733-32-0
Molecular Formula	C20H22ClNO4
Molecular Weight	375.85 g/mol
Synonyms	Benzyl 1,2,3,4-tetrahydro-6,7-dimethoxy-3-isoquinolinecarboxylate hydrochloride; 3-Carbobenzyloxy-1,2,3,4-tetrahydro-6,7-dimethoxyisoquinoline hydrochloride; 6,7-Dimethoxy-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic Acid Benzyl Ester Hydrochloride; 3-CBZ-6,7-Dimethoxytetrahydroisoquinoline HCl; NSC 339587; Benzyl 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylate hydrochloride
EINECS	Contact for details

Quality Control

Our 1,2,3,4-Tetrahydro-6,7-Dimethoxy-3-Isoquinolinecarboxylic Acid Phenylmethyl Ester Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical R&D and process chemistry. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%; Any single impurity ≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.