Description

Bis(2-Hydroxyethyl)-D8-Amine is a deuterated analog of diethanolamine, where eight hydrogen atoms are replaced with deuterium, a stable isotope of hydrogen. This deuteration is critical for applications requiring non-radioactive isotopic labeling, such as internal standards for mass spectrometry, which dramatically improves analytical accuracy and reliability. This high-purity compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors who require precise molecular tracking and metabolic studies.

Application

• Internal Standard for Mass Spectrometry (MS): Serves as a crucial quantitative reference standard in LC-MS and GC-MS analysis for quantifying non-deuterated diethanolamine and related compounds in complex matrices.
• Pharmaceutical Research & Metabolism Studies: Used as a deuterated tracer to investigate the pharmacokinetics, metabolic pathways, and degradation products of active pharmaceutical ingredients (APIs) and excipients.
• Deuterated Reagent Synthesis: Acts as a key building block for synthesizing more complex deuterated molecules, surfactants, or ligands used in specialized chemical and material research.
• NMR Spectroscopy Solvent & Reagent: Employed in nuclear magnetic resonance (NMR) spectroscopy to minimize proton signal interference, providing clearer spectral data for structural analysis.
• Agrochemical Analysis: Utilized in environmental and residue testing to accurately measure levels of diethanolamine-based compounds in soil, water, and crop samples.
• Polymer & Material Science: Incorporated into polymers or surface-active agents to study molecular dynamics, diffusion rates, and material properties using isotopic labeling techniques.

Basic Information

Product Name	Bis(2-Hydroxyethyl)-D8-Amine
CAS No.	103691-51-6
Molecular Formula	C4D8H3NO2
Molecular Weight	113.17 g/mol (deuterated form)
Synonyms	Diethanolamine-d8; 2,2'-Iminobis[ethanol-d4]; DEA-d8; Bis(2-hydroxyethyl-d4)amine; Dideutero-diethanolamine (fully deuterated on ethyl); N,N-Bis(2-hydroxyethyl-d4)amine; Deuteronated DEA; Isotopic Labeled Diethanolamine
EINECS	Contact for details

Quality Control

Our Bis(2-Hydroxyethyl)-D8-Amine is produced under strict quality management systems to ensure exceptional isotopic and chemical purity, which is paramount for analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as isotopic purity (D-enrichment), chemical purity by NMR and HPLC, and residual solvent content. We adhere to relevant industry standards for high-purity reagents and can provide material for GLP/GMP-regulated studies upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation and moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Chemical Purity (HPLC/NMR)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.