Description

1-o-Trityl-Sn-Glycero-3-Phosphocholine is a high-purity, synthetic phospholipid derivative, specifically a protected phosphatidylcholine precursor, widely used in advanced biochemical and pharmaceutical research. This compound is critical for the synthesis of complex lipid molecules and membrane mimetics, offering researchers a versatile building block with defined stereochemistry. It is primarily utilized by scientists and manufacturers in the fields of lipidomics, drug delivery systems (liposomes), and membrane biophysics.

Application

• Phospholipid Synthesis: A key protected intermediate in the chemical and enzymatic synthesis of phosphatidylcholines and other glycerophospholipids.
• Liposome & Nanoparticle Production: Used in the research and development of liposomal drug delivery vehicles and lipid nanoparticles (LNPs) for targeted therapeutics.
• Biochemical Research: Serves as a substrate or precursor in enzymatic studies involving phospholipases and lipid-modifying enzymes.
• Membrane Protein Studies: Employed in the reconstitution of membrane proteins and the creation of model membrane systems for biophysical analysis.
• Diagnostic Reagents: Can be utilized in the formulation of specialized reagents for clinical diagnostics and assays.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in lipid analysis.

Basic Information

Product Name	1-o-Trityl-Sn-Glycero-3-Phosphocholine
CAS No.	103675-56-5
Molecular Formula	C₃₂H₄₂NO₆P
Molecular Weight	567.65 g/mol
Synonyms	1-O-Trityl-sn-glycero-3-phosphocholine; Trityl-GPC; 1-O-(Triphenylmethyl)-sn-glycero-3-phosphocholine; (2R)-2-Hydroxy-3-(triphenylmethoxy)propyl 2-(trimethylammonio)ethyl phosphate; sn-3-O-Phosphocholine-1-O-tritylglycerol; PC(Trityl); Trityl-protected LysoPC; Lysophosphatidylcholine, 1-O-trityl derivative
EINECS	Contact for details

Quality Control

Our 1-o-Trityl-Sn-Glycero-3-Phosphocholine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided to guarantee the material meets the stringent requirements for research and pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in chloroform, methanol; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.