Description

Thiochroman-3-Ylamine Hydrochloride is a high-purity organic salt compound, serving as a critical synthetic intermediate in advanced pharmaceutical research and development. Its value lies in providing a reliable and consistent building block for constructing complex molecular architectures, particularly those containing the thiochroman scaffold. This product is essential for medicinal chemists and R&D teams in the pharmaceutical, agrochemical, and fine chemical industries who are developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, cardiovascular diseases, and other therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to explore new chemical entities.
• Agrochemical Synthesis: Intermediate in the development of novel herbicides, fungicides, or insecticides that utilize heterocyclic amine chemistry.
• Fine Chemical Production: Serves as a precursor for the manufacture of specialty chemicals, dyes, and functional materials.
• Academic & Institutional R&D: Utilized in university and research institute laboratories for methodological studies and novel synthetic route development.
• Chemical Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	Thiochroman-3-Ylamine Hydrochloride
CAS No.	103659-74-1
Molecular Formula	C9H12ClNS
Molecular Weight	201.71 g/mol
Synonyms	3-Thiochromanamine hydrochloride; 3-Aminothiochroman hydrochloride; 1-Thia-4-azaspiro[4.5]decan-3-amine hydrochloride (related structure); Thiochroman-3-amine HCl; 3,4-Dihydro-2H-1-benzothiopyran-3-amine hydrochloride; 2,3-Dihydro-1-benzothiopyran-3-amine hydrochloride; Benzo[b]thiophene-3-amine derivative (core); Contact for additional aliases.
EINECS	Contact for details

Quality Control

Our Thiochroman-3-Ylamine Hydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.