Description

n-Methyl-3-(Phenylthio)-1H-Indole-5-Methanesulfonamide is a specialized indole-based sulfonamide derivative, serving as a crucial advanced intermediate in modern organic synthesis. Its unique molecular structure, featuring both indole and sulfonamide pharmacophores, makes it a valuable building block for research and development in medicinal chemistry. This compound is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing novel therapeutic agents, particularly in areas requiring complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Biochemical Tool Compound: Potential use in developing probes for studying enzyme inhibition or receptor modulation due to its sulfonamide group.
• Fine Chemical Synthesis: Intermediate for the production of more complex, high-value specialty chemicals and agrochemicals.
• Academic Research: Employed in universities and research institutes for methodological development in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	n-Methyl-3-(Phenylthio)-1H-Indole-5-Methanesulfonamide
CAS No.	103654-21-3
Molecular Formula	C₁₆H₁₆N₂O₂S₂
Molecular Weight	332.44 g/mol
Synonyms	1H-Indole-5-methanesulfonamide, N-methyl-3-(phenylthio)-; 3-(Phenylthio)-N-methyl-1H-indole-5-methanesulfonamide; 5-[(Aminosulfonyl)methyl]-N-methyl-3-(phenylthio)-1H-indole; N-Methyl-3-(phenylthio)indole-5-methanesulfonamide; 103654-21-3; 3-Phenylsulfanyl-1-methyl-1H-indole-5-methanesulfonamide
EINECS	Contact for details

Quality Control

Our n-Methyl-3-(Phenylthio)-1H-Indole-5-Methanesulfonamide is produced under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as identity, purity, and impurity profiles. Our quality commitment aligns with the standards expected by the pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.