Description

7,8-Dihydroisoquinolin-5(6H)-One, Hydrochloride is a high-purity organic salt, serving as a critical building block in advanced pharmaceutical synthesis and fine chemical research. Its value lies in its role as a versatile synthetic intermediate for constructing complex nitrogen-containing heterocycles, which are core structures in many active pharmaceutical ingredients (APIs). This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing new therapeutic agents and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of isoquinoline-based drug candidates, including potential central nervous system (CNS) agents and antimicrobials.
• Agrochemical Research: Used in the development of novel herbicides and pesticides that leverage the isoquinoline scaffold for biological activity.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex polycyclic frameworks and alkaloid analogs.
• Chemical Biology Probe Development: Serves as a starting material for creating molecular probes to study enzyme function and biological pathways.
• Material Science Applications: Investigated as a monomer or precursor for specialty polymers and advanced organic electronic materials.

Basic Information

Product Name	7,8-Dihydroisoquinolin-5(6H)-One, Hydrochloride
CAS No.	103441-65-2
Molecular Formula	C9H10ClNO
Molecular Weight	183.63 g/mol
Synonyms	5,6,7,8-Tetrahydroisoquinolin-5-one hydrochloride; 5,6,7,8-Tetrahydro-5-isoquinolinone hydrochloride; 7,8-Dihydro-5(6H)-isoquinolinone hydrochloride; 5-Oxo-5,6,7,8-tetrahydroisoquinoline hydrochloride; 5,6,7,8-Tetrahydroisoquinolin-5-ol hydrochloride (tautomer); 5-Hydroxy-5,6,7,8-tetrahydroisoquinoline hydrochloride; 103441-65-2 (CAS)
EINECS	Contact for details

Quality Control

Our 7,8-Dihydroisoquinolin-5(6H)-One, Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.