Description

Pentafluoroethylphosphonic Acid Dichloride is a highly reactive organophosphorus intermediate characterized by its pentafluoroethyl group and acid dichloride functionality. This compound is critical for introducing the unique pentafluoroethylphosphonate moiety into target molecules, offering enhanced lipophilicity and metabolic stability. It is primarily sought after by researchers and manufacturers in the agrochemical and pharmaceutical industries for the synthesis of advanced active ingredients and novel chemical entities.

Application

• Agrochemical Intermediate: Key building block for synthesizing novel herbicides, insecticides, and fungicides with improved activity and environmental profiles.
• Pharmaceutical Synthesis: Used in the development of active pharmaceutical ingredients (APIs), particularly for incorporating fluorine-containing groups to modulate bioavailability and binding affinity.
• Ligand and Catalyst Preparation: Serves as a precursor for specialized phosphonate-based ligands used in catalysis and material science.
• Flame Retardant Research: Investigated as a potential intermediate for advanced, halogenated flame retardant additives.
• Surface Modification Agent: Employed to create specialized coatings or modify material surfaces with fluorinated phosphonate layers.
• Chemical Research & Development: A versatile reagent for organic synthesis, enabling the exploration of new chemical spaces in fluorinated organophosphorus chemistry.

Basic Information

Product Name	Pentafluoroethylphosphonic Acid Dichloride
CAS No.	103304-97-8
Molecular Formula	C2HF5Cl2O2P
Molecular Weight	246.90 g/mol
Synonyms	Phosphonic acid, P,P-dichloro-, 2,2,2-trifluoroethyl ester; (Pentafluoroethyl)phosphonic dichloride; 2,2,2-Trifluoroethylphosphonic dichloride; C2F5P(O)Cl2; Pentafluoroethanephosphonyl Dichloride; Pentafluoroethylphosphonyl Dichloride; Dichloro(pentafluoroethyl)phosphine Oxide
EINECS	Contact for details

Quality Control

Our Pentafluoroethylphosphonic Acid Dichloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including NMR, GC, and HPLC, to verify identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic and strong acid/organic solvent nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Keep away from heat, open flames, and incompatible materials such as bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.