Description

Cyclopropane, 1-Chloro-2-Ethyl-1-Ethynyl-, trans- (9Ci) is a specialized halogenated cyclopropane derivative with a unique molecular architecture, serving as a high-value synthetic intermediate. This compound is particularly valued for its rigid, strained three-membered ring structure and reactive functional groups, which enable precise stereochemical control in complex organic syntheses. It is primarily sought by research chemists and process development scientists in the pharmaceutical and advanced materials sectors for constructing novel molecular scaffolds and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) and anti-infective agents.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the cyclopropane ring contributes to biological activity and environmental stability.
• Advanced Material Synthesis: Serves as a precursor for functionalized polymers and liquid crystals, leveraging its rigid geometry to influence material properties.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for cyclopropanation reactions, ring-opening polymerizations, and as a ligand in catalytic systems.
• Chemical Biology Probe: Utilized in the design of molecular probes and tags to study biological systems and enzyme mechanisms due to its reactive alkyne and halogen moieties.

Basic Information

Product Name	Cyclopropane, 1-Chloro-2-Ethyl-1-Ethynyl-, trans- (9Ci)
CAS No.	103304-33-2
Molecular Formula	C7H9Cl
Molecular Weight	128.60 g/mol
Synonyms	trans-1-Chloro-2-ethyl-1-ethynylcyclopropane; 1-Chloro-2-ethyl-1-ethynylcyclopropane, trans-; (1R,2S)-1-Chloro-2-ethyl-1-ethynylcyclopropane; (1S,2R)-1-Chloro-2-ethyl-1-ethynylcyclopropane; NSC 406911; 1-Ethynyl-2-ethyl-1-chlorocyclopropane, trans-; Halogenated Cyclopropane Derivative
EINECS	Contact for details

Quality Control

Our Cyclopropane, 1-Chloro-2-Ethyl-1-Ethynyl-, trans- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatography (GC/HPLC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing batch-specific results are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong bases and incompatible organic solvents. Due to its light-sensitive nature, containers should be amber glass or suitably opaque.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC)	≥ 95.0% (Area %)
Purity (HPLC)	≥ 95.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.