Description

cis-4-tert-Butyldimethylsilyloxycyclohexanol is a high-value organosilicon-protected intermediate, specifically designed for advanced synthetic chemistry applications. This compound is critical for its role as a versatile chiral building block, offering precise stereochemical control in complex molecule assembly. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides requiring specific stereochemistry.
• Asymmetric Catalysis Research: Serves as a substrate or ligand precursor in the development of new catalytic systems.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances where high purity and defined stereochemistry are essential.
• Academic & Industrial R&D: A valuable tool for synthetic organic chemists in methodology development and total synthesis projects.

Basic Information

Product Name	cis-4-tert-Butyldimethylsilyloxycyclohexanol
CAS No.	103202-62-6
Molecular Formula	C₁₂H₂₆O₂Si
Molecular Weight	230.42 g/mol
Synonyms	cis-4-[(tert-Butyldimethylsilyl)oxy]cyclohexanol; 4-[(1,1-Dimethylethyl)dimethylsilyl]oxy]-cis-cyclohexanol; 4-(tert-Butyldimethylsiloxy)cyclohexanol (cis); TBDMS-protected cis-4-hydroxycyclohexanol; cis-4-Hydroxycyclohexyl tert-butyldimethylsilyl ether; cis-4-TBDMS-oxycyclohexanol; cis-4-O-TBDMS-cyclohexanol
EINECS	Contact for details

Quality Control

Our cis-4-tert-Butyldimethylsilyloxycyclohexanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical and isomeric purity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Isomeric Purity (cis-isomer)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.