Description

2-(2-tert-Butoxycarbonylaminothiazol-4-Yl)-2-Pentenedioic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its specific thiazole and glutaconic acid derivative structure. This compound is critical for the synthesis of complex molecules, offering a versatile building block for constructing active pharmaceutical ingredients (APIs) with precise stereochemistry and functional groups. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel therapeutic agents and crop protection products.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex APIs, particularly for antibiotics and other bioactive molecules containing a thiazole moiety.
• Antibiotic Research & Development: Serves as a crucial precursor in the development of next-generation cephalosporin and penicillin derivatives.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides that require specific heterocyclic structures for activity.
• Chemical Biology & Proteomics: Employed as a specialized reagent for modifying peptides and proteins, or for creating activity-based probes.
• Organic Synthesis Research: Provides a versatile scaffold for academic and industrial research into new chemical reactions and methodologies.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	2-(2-tert-Butoxycarbonylaminothiazol-4-Yl)-2-Pentenedioic Acid
CAS No.	103054-22-4
Molecular Formula	C₁₃H₁₆N₂O₆S
Molecular Weight	328.34 g/mol
Synonyms	2-[(2-{[(1,1-Dimethylethoxy)carbonyl]amino}-1,3-thiazol-4-yl)]-2-pentenedioic acid; 2-(2-(tert-Butoxycarbonylamino)thiazol-4-yl)pent-2-enedioic acid; Boc-Amino-Thiazole-Glutaconic Acid; (2E)-2-[2-[(tert-Butoxycarbonyl)amino]-1,3-thiazol-4-yl]pent-2-enedioic acid; 103054-22-4; tert-Butyl N-(4-[(1E)-3-carboxyprop-1-en-2-yl]-1,3-thiazol-2-yl)carbamate (glutaconic acid form)
EINECS	Contact for details

Quality Control

Every batch of 2-(2-tert-Butoxycarbonylaminothiazol-4-Yl)-2-Pentenedioic Acid is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.