Description

Diazald-n-Methyl-13C-n-Methyl-D3 CAS NO 102832-11-1 is a stable isotope-labeled derivative of Diazald (N-Methyl-N-nitroso-p-toluenesulfonamide), a widely used reagent for the safe generation of diazomethane. This compound is specifically enriched with carbon-13 and deuterium isotopes, making it an essential tool for precise analytical and research applications. It is primarily used by scientists and quality control professionals in pharmaceutical development, environmental analysis, and advanced organic synthesis who require high-fidelity internal standards for mass spectrometry and metabolic studies.

Application

• Internal Standard for Mass Spectrometry (MS): Serves as a critical quantitative reference standard in LC-MS and GC-MS analysis for method development and validation.
• Metabolic Pathway Tracing: Used in pharmacokinetic and drug metabolism studies to track the fate of methyl groups using 13C and D labels.
• Methylation Reaction Studies: Enables the detailed mechanistic study of methylation reactions and diazomethane chemistry in synthetic organic research.
• Pharmaceutical Impurity Profiling: Assists in the identification and quantification of process-related impurities and degradants in active pharmaceutical ingredients (APIs).
• Environmental Analysis: Applied as a labeled standard in the analysis of esters, carboxylic acids, and phenols in complex matrices like water and soil.
• Stable Isotope Labeling: A key precursor for the synthesis of other complex molecules labeled with stable isotopes for research purposes.

Basic Information

Product Name	Diazald-n-Methyl-13C-n-Methyl-D3
CAS No.	102832-11-1
Molecular Formula	C9H9D313CN2O2S
Molecular Weight	Contact for details
Synonyms	N-Methyl-13C,N-methyl-d3-N-nitroso-p-toluenesulfonamide; [13C]D3]-Diazald; Labeled Diazald; N-Methyl-N-nitroso-p-toluenesulfonamide-13C,d3; N-Methyl-d3-N-nitroso-4-methylbenzenesulfonamide-N-13C; Isotopically Labeled Diazald; MSTFA-d3-13C precursor; Stable Isotope Labeled Methylating Agent.
EINECS	Contact for details

Quality Control

Our Diazald-n-Methyl-13C-n-Methyl-D3 is manufactured under strict quality protocols to ensure exceptional isotopic purity and chemical integrity. Each batch is analyzed using advanced techniques including NMR and High-Resolution Mass Spectrometry to confirm isotopic enrichment and chemical purity. A comprehensive Certificate of Analysis (COA) detailing isotopic purity, chemical purity, and solvent content is provided with every shipment, supporting compliance with cGMP and research-grade material standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the container to reach room temperature before opening to minimize moisture absorption. Keep under an inert atmosphere for long-term storage to preserve stability.

Specification

Item	Specification
Appearance	White to pale yellow crystalline solid
Identification (NMR)	Conforms to structure
Isotopic Purity (13C)	≥ 99 atom %
Isotopic Purity (D)	≥ 98 atom % (D3)
Chemical Purity (HPLC)	≥ 98.0%
Solvent Content (Residue on Evaporation)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.