Description

2-Chloro-1,3-Difluoropropane is a versatile halogenated hydrocarbon intermediate with unique chemical reactivity. This compound is valued for its role as a key building block in the synthesis of more complex fluorinated molecules, offering a balance of reactivity and stability. It is primarily utilized by research and development chemists, process engineers, and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of modern pesticides and herbicides, where the introduction of fluorine atoms can improve efficacy and environmental profile.
• Fluorinated Polymer & Material Science: Acts as a monomer or modifying agent in the development of specialty polymers, coatings, and surfactants with unique properties like oil and water repellency.
• Organic Synthesis Building Block: Employed in research laboratories for nucleophilic substitution and coupling reactions to introduce chlorodifluoropropyl groups into target molecules.
• Refrigerant & Propellant Formulation: Investigated as a potential component in next-generation, low-global-warming-potential (GWP) refrigerant blends.
• Electrolyte Additive for Batteries: Explored for use in lithium-ion battery electrolytes to improve performance and safety characteristics.

Basic Information

Product Name	2-Chloro-1,3-Difluoropropane
CAS No.	102738-79-4
Molecular Formula	C3H5ClF2
Molecular Weight	114.52 g/mol
Synonyms	1,3-Difluoro-2-chloropropane; 2-Chloro-1,3-difluoropropane; Propane, 2-chloro-1,3-difluoro-; 2-Chloropropane-1,3-difluoride; 1,3-Difluoro-2-chloro-propane; Chlorodifluoropropane; HCFC-252; R-252
EINECS	Contact for details

Quality Control

Our 2-Chloro-1,3-Difluoropropane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials such as strong bases and reactive metals. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use. Recommended storage temperature is 2-25°C.

Specification

Item	Specification
Appearance	Colorless clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Density (20°C)	1.25 - 1.35 g/mL
Boiling Point	~ 70 - 75 °C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.