Description

trans-1-Chloro-3,3,3-Trifluoroprop-1-Ene is a halogenated olefin building block of significant industrial interest, primarily valued for its unique combination of chlorine and fluorine atoms on an alkene backbone. This structure makes it a versatile intermediate for synthesizing advanced fluorinated compounds, where it introduces both reactivity and desirable physicochemical properties. It is particularly sought after by R&D and production chemists in the pharmaceutical, agrochemical, and specialty chemical sectors for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of fluorinated drug candidates, leveraging the fluorine atom's ability to modulate bioavailability, metabolic stability, and binding affinity.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the trifluoromethyl group enhances lipophilicity and biological activity.
• Fluorinated Polymer & Material Science: Acts as a monomer or modifier in the synthesis of specialty polymers, coatings, and elastomers with improved chemical resistance, thermal stability, and surface properties.
• Refrigerant & Propellant Formulation: Investigated as a potential component in next-generation, low-global-warming-potential (GWP) refrigerant blends due to its volatile nature.
• Organic Synthesis Building Block: Employed in various name reactions (e.g., Heck coupling, hydrohalogenation) to construct complex fluorinated molecules for research and fine chemical production.
• Electronic Chemicals: Used in the plasma etching processes for semiconductor manufacturing or as a precursor for dielectric fluids.

Basic Information

Product Name	trans-1-Chloro-3,3,3-Trifluoroprop-1-Ene
CAS No.	102687-65-0
Molecular Formula	C3H2ClF3
Molecular Weight	130.49 g/mol
Synonyms	(E)-1-Chloro-3,3,3-trifluoropropene; trans-1-Chloro-3,3,3-trifluoropropene; 1-Chloro-3,3,3-trifluoro-1-propene (trans); (E)-1-Chloro-3,3,3-trifluoro-1-propene; trans-3,3,3-Trifluoro-1-chloropropene; HCFO-1233zd(E); Solstice® 1233zd (E) (Honeywell trade name); Forane® 1233zd (E) (Arkema trade name)
EINECS	Contact for details

Quality Control

Our trans-1-Chloro-3,3,3-Trifluoroprop-1-Ene is manufactured under stringent quality management systems. Every batch undergoes rigorous analytical testing, including GC, GC-MS, NMR, and Karl Fischer titration, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our production adheres to cGMP principles where applicable, ensuring reliability for demanding applications in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, containers must be kept tightly sealed and upright to prevent leakage and pressure build-up. Recommended storage temperature is 2-8°C for long-term stability, though short-term storage at controlled room temperature (15-25°C) is acceptable.

Specification

Item	Specification
Appearance	Colorless clear liquid
Identification (IR)	Conforms
Purity (GC)	≥ 99.0%
trans-Isomer Content (GC)	≥ 99.5%
Water Content (KF)	≤ 50 ppm
Non-volatile Residue	≤ 0.01%
Acidity (as HCl)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.