Description

2-[4-(4-Chlorophenyl)-2-[(2-Methoxyphenyl)Methylamino]-1,3-Thiazol-5-Y L]Acetic Acid is a high-purity, non-racemic synthetic intermediate of significant importance in advanced pharmaceutical research and development. This compound, with CAS NO 102612-89-5, is valued for its specific molecular architecture, which makes it a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for creating targeted therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Chemical Reference Standard: Used as a certified reference material (CRM) for analytical method development, validation, and quality control in pharmaceutical laboratories.
• Process Chemistry Research: Employed in route scouting and optimization studies for the scalable production of complex target molecules.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies and the generation of focused compound libraries.
• Academic Research: Utilized in university and institutional labs for studies in organic synthesis, heterocyclic chemistry, and pharmacology.

Basic Information

Product Name	2-[4-(4-Chlorophenyl)-2-[(2-Methoxyphenyl)Methylamino]-1,3-Thiazol-5-Y L]Acetic Acid
CAS No.	102612-89-5
Molecular Formula	C19H17ClN2O3S
Molecular Weight	388.87 g/mol
Synonyms	2-[4-(4-Chlorophenyl)-2-[(2-methoxyphenyl)methylamino]-1,3-thiazol-5-yl]acetic acid; (5-Carboxymethyl-4-(4-chlorophenyl)-2-[(2-methoxyphenyl)methylamino]thiazole); 102612-89-5; 2-{4-(4-Chlorophenyl)-2-[(2-methoxyphenyl)(methyl)amino]-1,3-thiazol-5-yl}acetic acid; 5-Thiazoleacetic acid, 4-(4-chlorophenyl)-2-[[(2-methoxyphenyl)methyl]amino]-
EINECS	Contact for details

Quality Control

Our 2-[4-(4-Chlorophenyl)-2-[(2-Methoxyphenyl)Methylamino]-1,3-Thiazol-5-Y L]Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity, to ensure compliance with exacting R&D and process chemistry standards. Comprehensive Certificates of Analysis (COA) detailing identity, assay, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.