Description

5-(Hexyloxy)Psoralen is a synthetic derivative of psoralen, a naturally occurring furocoumarin compound. This chemical is valued for its ability to intercalate with DNA and cross-link upon exposure to ultraviolet A (UVA) light, making it a critical component in photochemotherapy and photobiological research. It is primarily utilized by pharmaceutical researchers, material scientists, and manufacturers in the life sciences sector for developing targeted therapies and advanced photoresponsive materials.

Application

• Photochemotherapy (PUVA) Research: A key intermediate in the development of novel psoralen-based drugs for treating skin conditions like psoriasis, vitiligo, and cutaneous T-cell lymphoma.
• Photobiology Studies: Used as a precise molecular tool to study DNA-protein interactions, cell cycle arrest, and apoptosis mechanisms triggered by photoactivation.
• Material Science: Serves as a photo-crosslinking agent in the synthesis of smart polymers, hydrogels, and surface coatings that respond to light stimuli.
• Chemical Synthesis: Acts as a versatile building block for creating more complex furocoumarin derivatives with tailored biological activity and photophysical properties.
• Analytical Standards: Employed as a high-purity reference standard in HPLC and LC-MS methods for quality control and pharmacokinetic studies of related pharmaceutical compounds.

Basic Information

Product Name	5-(Hexyloxy)Psoralen
CAS No.	102416-40-0
Molecular Formula	C19H22O4
Molecular Weight	314.38 g/mol
Synonyms	5-Hexyloxypsoralen; 5-Hexyloxyfuro[3,2-g]chromen-7-one; 5-(Hexyloxy)-7H-furo[3,2-g][1]benzopyran-7-one; 5-HOP; 5-n-Hexyloxypsoralen; Bergapten hexyl ether; 5-Hexyloxy-7H-furo[3,2-g]chromen-7-one
EINECS	Contact for details

Quality Control

Our 5-(Hexyloxy)Psoralen is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent control of residual solvents and heavy metals. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature of 15-25°C. The material is light-sensitive and easily oxidized; prolonged exposure to air, light, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.