Description

6,7-Dimethoxy-2-[2-(3,4,5,6-Tetrahydro-2H-Pyridin-1-Yl)Ethyl]-3,4-Dihydro-1H-Isoquinoline Dichloride is a high-purity synthetic intermediate of significant interest in advanced pharmaceutical research and development. This compound is valued for its complex heterocyclic structure, which serves as a critical building block in the synthesis of novel bioactive molecules. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of central nervous system (CNS) agents and other therapeutic candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting neurological pathways.
• Chemical Research & Development: Used as a sophisticated building block in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Academic Research: Employed in university and institutional labs for studying heterocyclic chemistry and synthesizing novel compound libraries.
• Process Chemistry: Utilized in scaling up synthetic routes during the preclinical and early development phases of new chemical entities (NCEs).

Basic Information

Product Name	6,7-Dimethoxy-2-[2-(3,4,5,6-Tetrahydro-2H-Pyridin-1-Yl)Ethyl]-3,4-Dihydro-1H-Isoquinoline Dichloride
CAS No.	102395-78-8
Molecular Formula	C₁₈H₂₇Cl₂N₂O₂
Molecular Weight	374.33 g/mol
Synonyms	6,7-Dimethoxy-2-[2-(3,4,5,6-tetrahydro-2H-pyridin-1-yl)ethyl]-1,2,3,4-tetrahydroisoquinoline dihydrochloride; 1,2,3,4-Tetrahydro-6,7-dimethoxy-2-[2-(1-piperidinyl)ethyl]isoquinoline dihydrochloride; 6,7-Dimethoxy-2-[2-(piperidino)ethyl]-1,2,3,4-tetrahydroisoquinoline dihydrochloride; 102395-78-8; UNII-9Q9K3S001L; CHEMBL3183452; DTXSID60622376
EINECS	Contact for details

Quality Control

Our 6,7-Dimethoxy-2-[2-(3,4,5,6-Tetrahydro-2H-Pyridin-1-Yl)Ethyl]-3,4-Dihydro-1H-Isoquinoline Dichloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.