Description

Malonic-13C3 Acid is a stable isotope-labeled derivative of malonic acid, where all three carbon atoms are the carbon-13 isotope. This high-purity labeled compound is essential for advanced analytical research, providing a critical internal standard for precise quantitative analysis. It is primarily utilized by research scientists and analytical chemists in pharmaceutical development, metabolic studies, and environmental tracer analysis to ensure accuracy and reliability in mass spectrometry and NMR spectroscopy.

Application

• Internal Standard for Mass Spectrometry (MS): Used for the accurate quantification of malonic acid and related metabolites in complex biological matrices like plasma, urine, and tissue samples.
• Metabolic Pathway Tracing: Serves as a crucial tracer in 13C metabolic flux analysis (13C-MFA) to study central carbon metabolism in cells, bacteria, and plants.
• Pharmaceutical Research & Development: Employed in drug metabolism and pharmacokinetics (DMPK) studies to track the fate of drug molecules and their metabolites.
• NMR Spectroscopy: Acts as a chemical shift reference or a building block for synthesizing more complex 13C-labeled compounds for structural elucidation.
• Environmental Science: Applied as a tracer to study the degradation pathways of organic compounds in environmental systems.
• Synthesis of Labeled Compounds: A key starting material for the synthesis of other 13C-labeled fine chemicals, intermediates, and active pharmaceutical ingredients (APIs).

Basic Information

Product Name	Malonic-13C3 Acid
CAS No.	102342-85-8
Molecular Formula	13C3H4O4
Molecular Weight	108.04 g/mol
Synonyms	1,3-13C2-Propanedioic Acid; Malonic-13C3 Acid; 13C3-Malonic Acid; Propanedioic-13C3 Acid; Dicarbomethoxy-13C3 Methane; Carboxyacetic-13C3 Acid; Methanedicarboxylic-13C3 Acid; Isotopic Labeled Malonic Acid
EINECS	Contact for details

Quality Control

Our Malonic-13C3 Acid is manufactured under strict quality control protocols to ensure exceptional isotopic and chemical purity, critical for sensitive analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment, chemical purity, and relevant spectroscopic data. We adhere to industry best practices to guarantee batch-to-batch consistency and reliability for your research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Isotopic Enrichment	≥ 99 atom % 13C
Chemical Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.