Description

4-Ethynyl-1H-Indole is a versatile and high-value heterocyclic building block featuring both indole and alkyne functional groups. This unique molecular architecture makes it a critical intermediate for the synthesis of complex pharmacologically active compounds. It is primarily sought after by research institutions and pharmaceutical companies engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Medicinal Chemistry Research: Used extensively in structure-activity relationship (SAR) studies and combinatorial chemistry libraries due to its reactive ethynyl moiety.
• Agrochemical Development: Serves as a building block for creating new active ingredients with potential fungicidal or insecticidal properties.
• Material Science: Employed in the development of advanced organic electronic materials and polymers via click chemistry and other coupling reactions.
• Bioconjugation: The alkyne group allows for efficient labeling and conjugation of biomolecules in probe and diagnostic reagent development.

Basic Information

Product Name	4-Ethynyl-1H-Indole
CAS No.	102301-81-5
Molecular Formula	C10H7N
Molecular Weight	141.17 g/mol
Synonyms	4-Ethynylindole; 1H-Indole-4-ethyne; 4-Ethynyl-1H-indole; 4-Ethynylindole; 4-(Ethynyl)-1H-indole; 102301-81-5; 4-Ethynylindole (6CI,7CI,8CI)
EINECS	Contact for details

Quality Control

Our 4-Ethynyl-1H-Indole is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable to support our clients' regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is light-sensitive and should be handled under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.