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(S)-(-)-1-(2,4,6-Triisopropylphenyl)Ethanol CAS NO 102225-88-7


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CAS No.:102225-88-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(S)-(-)-1-(2,4,6-Triisopropylphenyl)Ethanol is a high-value, chiral secondary alcohol featuring a sterically hindered triisopropylphenyl group. This compound is a crucial chiral building block and ligand precursor in asymmetric synthesis, prized for its ability to induce high enantioselectivity in catalytic reactions. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for the development of novel active ingredients and functional molecules.

Application

  • As a chiral ligand or ligand precursor in asymmetric metal-catalyzed reactions, such as hydrogenation and C-C bond formation.
  • As a key chiral intermediate in the synthesis of active pharmaceutical ingredients (APIs) and agrochemicals.
  • As a resolving agent or chiral auxiliary for the separation of enantiomers.
  • In academic and industrial research for developing new methodologies in stereoselective synthesis.
  • As a building block for advanced materials requiring specific chiral architectures.
  • For the preparation of chiral ionic liquids or organocatalysts.

Basic Information

Product Name (S)-(-)-1-(2,4,6-Triisopropylphenyl)Ethanol
CAS No. 102225-88-7
Molecular Formula C₁₇H₂₈O
Molecular Weight 248.40 g/mol
Synonyms (S)-1-(2,4,6-Triisopropylphenyl)ethanol; (S)-(-)-TIPPE; (S)-1-(2,4,6-Triisopropylphenyl)ethan-1-ol; (S)-α-(2,4,6-Triisopropylphenyl)ethyl alcohol; (S)-MTPA alcohol analog; (S)-1-(2,4,6-Triisopropylphenyl)ethyl alcohol; (S)-TIPAE; (-)-1-(2,4,6-Triisopropylphenyl)ethanol
EINECS Contact for details

Quality Control

Our (S)-(-)-1-(2,4,6-Triisopropylphenyl)Ethanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) and standard purity assays, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Keep away from heat and incompatible materials.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 98.0%
Enantiomeric Excess (Chiral HPLC) ≥ 99.0% ee
Melting Point Contact for details
Specific Rotation Contact for details
Heavy Metals < 10 ppm
Residual Solvents (GC) Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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