Description

Nemadectin is a potent 16-membered macrocyclic lactone belonging to the avermectin family, widely recognized for its exceptional anthelmintic and insecticidal properties. Its high efficacy and broad-spectrum activity make it a critical active ingredient in veterinary and agricultural formulations. This compound is essential for manufacturers developing advanced parasitic control solutions for livestock health and crop protection.

Application

• Primary active ingredient in veterinary endectocides for the control of internal and external parasites in livestock.
• Key component in agricultural insecticides and acaricides for protecting high-value crops.
• Used in animal health research and development of novel antiparasitic formulations.
• Intermediate in the synthesis of other macrocyclic lactone derivatives with enhanced biological activity.
• Formulation into pour-on, injectable, and feed additive products for livestock.
• Development of sustainable pest management programs in integrated farming systems.

Basic Information

Item	Details
Product Name	Nemadectin
CAS No.	102130-84-7
Molecular Formula	C38H58O11
Molecular Weight	690.87 g/mol
Synonyms	LL-F28249-α; 5-O-Demethyl-28-deoxy-6,28-epoxy-25-(1-methylpropyl)-6,28-dideoxy-5-(methoxycarbonyl)-13-epi-milbemycin β3; Nemadectin α; MK-0244; Avermectin B1 5-O-demethyl-28-deoxy-6,28-epoxy-25-(1-methylpropyl)-; LL-F28249α; (2aE,4E,8E)-5-[(1R,2S,5S,7S,8S,9S,10R,11S,13S,15R,17R,20S,21S,24S,25S)-21,24-Dihydroxy-10,11,14,15-tetrahydro-5'-demethyl-25-[(1S)-1-methylpropyl]-5'-(methoxycarbonyl)-2',3',4',5,6,7,8,9,10,11,13,15,17,20,21,24-hexadecahydro-12H-spiro[furan-2,13'-[13,27]epoxy[1,11]dioxacycloheptadecino[4,3-d]pyran]]-2,4,8-trimethyl-2,4,8-tridecatrienoic acid methyl ester
EINECS	Contact for details

Quality Control

Our Nemadectin is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and related substances, to meet the stringent requirements of the agrochemical and veterinary pharmaceutical industries. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.