Description

5,8-Dimethoxy-1,2,3,4-Tetrahydroisoquinolin-4-Ol Hydrochloride is a high-purity, synthetically derived organic compound belonging to the tetrahydroisoquinoline class, supplied as a hydrochloride salt for enhanced stability and handling. This compound serves as a critical pharmaceutical intermediate and a versatile building block in advanced organic synthesis, enabling the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is essential for research and development laboratories, process chemists, and manufacturers in the pharmaceutical, agrochemical, and life science sectors requiring a reliable source of this specialized intermediate.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex alkaloids and potential therapeutic agents targeting the central nervous system.
• Organic Synthesis Building Block: Utilized in the construction of complex molecular architectures for research and development purposes.
• Medicinal Chemistry Research: Employed in the discovery and optimization of new drug candidates, particularly those with isoquinoline-based scaffolds.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Agrochemical Synthesis: Used as an intermediate in the development of advanced crop protection agents and pesticides.
• Biochemical Research: Applied in studies investigating enzyme interactions and biochemical pathways involving isoquinoline derivatives.

Basic Information

Product Name	5,8-Dimethoxy-1,2,3,4-Tetrahydroisoquinolin-4-Ol Hydrochloride
CAS No.	102073-77-8
Molecular Formula	C₁₁H₁₅NO₃·HCl
Molecular Weight	245.70 g/mol
Synonyms	5,8-Dimethoxy-1,2,3,4-tetrahydro-4-isoquinolinol hydrochloride; 4-Hydroxy-5,8-dimethoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride; 5,8-Dimethoxy-1,2,3,4-tetrahydro-4-hydroxyisoquinoline hydrochloride; 1,2,3,4-Tetrahydro-5,8-dimethoxy-4-isoquinolinol hydrochloride; 4-Hydroxy-5,8-dimethoxytetrahydroisoquinoline HCl; 5,8-Dimethoxytetrahydroisoquinolin-4-ol HCl; THIQ derivative hydrochloride
EINECS	Contact for details

Quality Control

Our 5,8-Dimethoxy-1,2,3,4-Tetrahydroisoquinolin-4-Ol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical and research applications. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), identity confirmation (by IR, NMR), and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.