Description

Methyl 4-Iodo-3-Indolecarboxylate is a versatile halogenated indole derivative, a crucial synthetic intermediate in advanced organic chemistry. Its value lies in the strategic positioning of the iodine atom and ester functionality, enabling selective cross-coupling reactions and further functionalization. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, particularly for developing novel active ingredients and complex heterocyclic molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially kinase inhibitors and other biologically active indole-based compounds.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that leverage the indole scaffold.
• Material Science: Serves as a precursor for functionalized organic materials and ligands for catalytic systems.
• Chemical Synthesis: Enables Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to create complex molecular architectures.
• Academic & R&D: A valuable reagent for methodological studies and exploring new synthetic pathways in organic chemistry laboratories.

Basic Information

Product Name	Methyl 4-Iodo-3-Indolecarboxylate
CAS No.	101909-44-8
Molecular Formula	C10H8INO2
Molecular Weight	301.08 g/mol
Synonyms	Methyl 4-iodo-1H-indole-3-carboxylate; 4-Iodo-1H-indole-3-carboxylic acid methyl ester; 3-Carbomethoxy-4-iodoindole; 1H-Indole-3-carboxylic acid, 4-iodo-, methyl ester; Methyl 4-iodoindole-3-carboxylate
EINECS	Contact for details

Quality Control

Our Methyl 4-Iodo-3-Indolecarboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.