Description

D-Mannose-3-13C is a stable isotope-labeled analog of D-Mannose, specifically enriched with carbon-13 at the C-3 position. This compound is essential for advanced research and analytical applications where precise metabolic tracing and quantification are required. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and diagnostic manufacturers in the fields of metabolomics, glycobiology, and drug development studies.

Application

• Metabolic Pathway Tracing: Used as an internal standard or tracer in mass spectrometry (MS) and nuclear magnetic resonance (NMR) studies to investigate carbohydrate metabolism and glycosylation pathways.
• Quantitative Analysis: Serves as a critical standard for the accurate quantification of endogenous D-Mannose levels in complex biological matrices via LC-MS/MS or GC-MS.
• Pharmaceutical Research: Employed in the development and validation of assays for drugs targeting metabolic disorders, bacterial infections (e.g., UTI prevention), and glycosylation-related diseases.
• Diagnostic Reagent Manufacturing: Integrated into the production of high-precision diagnostic kits and calibrators for clinical laboratories.
• Nutritional Science Studies: Applied in research to study the absorption, distribution, and effects of dietary sugars and prebiotics.
• Biochemical Synthesis: Acts as a labeled building block for the synthesis of more complex isotopically labeled glycans, glycoproteins, or other biochemical probes.

Basic Information

Product Name	D-Mannose-3-13C
CAS No.	101615-89-8
Molecular Formula	C513CH12O6
Molecular Weight	181.15 g/mol (for 13C1 labeled form)
Synonyms	D-Mannose-3-13C; (3-13C)Mannose; Mannose-3-13C; 13C Labeled D-Mannose; D-(-)-Mannose-3-13C; Isotopic Mannose; [3-13C]-D-Mannopyranose; Stable Isotope-Labeled Mannose
EINECS	Contact for details

Quality Control

Our D-Mannose-3-13C is manufactured under strict quality management systems. Each batch is characterized to ensure high chemical purity and isotopic enrichment, typically exceeding 99% chemical purity and 99 atom % 13C. Comprehensive testing includes identification (IR, NMR), assay (HPLC), isotopic enrichment analysis (MS), and specific tests for residual solvents and impurities. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent absorption of water. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 99.0%
Isotopic Enrichment (MS)	≥ 99 atom % 13C
Specific Optical Rotation	-14.0° to -15.5° (c=4 in H2O)
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.