Description

2-Benzyl-3-(Chloromethyl)-3,4-Dihydro-1H-Isoquinoline Chloride is a versatile organic salt and a key synthetic intermediate in advanced chemical manufacturing. Its unique fused-ring structure with reactive chloromethyl and benzyl groups makes it a valuable building block for constructing complex nitrogen-containing heterocycles. This compound is primarily sought by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of complex isoquinoline-based drug candidates and bioactive molecules.
• Organic Synthesis Building Block: Used for constructing nitrogen heterocycles, spiro compounds, and other complex molecular architectures in medicinal chemistry research.
• Agrochemical Research: Employed in the development of new pesticides and herbicides that utilize the isoquinoline scaffold for biological activity.
• Material Science: Investigated as a monomer or precursor for functional polymers and advanced organic materials.
• Catalyst Ligand Synthesis: Potential use in the preparation of novel chiral or non-chiral ligands for catalytic applications.

Basic Information

Product Name	2-Benzyl-3-(Chloromethyl)-3,4-Dihydro-1H-Isoquinoline Chloride
CAS No.	101573-65-3
Molecular Formula	C17H17Cl2N
Molecular Weight	306.23 g/mol
Synonyms	1H-Isoquinoline, 3,4-dihydro-2-(phenylmethyl)-3-(chloromethyl)-, hydrochloride; 2-Benzyl-3-(chloromethyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride; 3,4-Dihydro-2-(phenylmethyl)-3-(chloromethyl)-1H-isoquinoline hydrochloride; 2-Benzyl-3-chloromethyl-1,2,3,4-tetrahydroisoquinoline HCl; 101573-65-3; BCMIQ-Cl
EINECS	Contact for details

Quality Control

Our 2-Benzyl-3-(Chloromethyl)-3,4-Dihydro-1H-Isoquinoline Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider inert atmosphere conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.